SHARE YOUR RESULTS, HELP SAVE LIVES

If you are BRCA positive, there is a 50% chance that each of your children is also BRCA positive. In addition, this means other members of your family (mother, father, sisters, brothers, aunts, uncles, cousins) may also be BRCA positive and may not know. Share this life-saving knowledge with your family and friends and encourage them to get tested. You have the power to save lives.

Haleigh Youtie Talks Her Mom’s Legacy And Breast Cancer Awareness

For Haleigh Youtie, her life halted 6-months ago when she lost her mother, Eileen after an 8-year battle with breast cancer. Over her 8 year-long fight Eileen made it her mission to get all Ashkenazi Jews tested for a Breast Cancer Gene mutation, as she had the BRCA1 gene mutation herself. According to statistics, 1 in 40 Ashkenazi Jews carries a mutation of a BRCA gene, most without knowing.

Source: OceanDrive

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Sharsheret and Yodeah Educate Women About Breast Cancer

In honor of Women’s History Month, our Women’s Philanthropy division wants you to know about Federation’s efforts to improve the lives of Jewish Women everywhere. Our Women’s Impact Initiative Grants are supporting two organizations that help Jewish women understand their risk of breast cancer: Sharsheret and Yodeah, which means “to know” in Hebrew.

Source: jewishmiami.org

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THE MOST RELEVANT GENES FOR COMMON HEREDITARY CANCERS

* CDK4: analysis is limited to chr12:g.58145429-58145431 (codon 24). EPCAM: analysis is limited to deletions that minimally encompass the 3′ end of the gene including exons 8 and/or 9. GREM1: analysis is limited to duplications that overlap the upstream regulatory region. MITF: analysis is limited to chr3:g.70014091 (including c.952G>A). MUTYH: single heterozygous pathogenic variants, likely pathogenic variants, and variants of uncertain significance are not reported. PMS2: variants of uncertain significance are not reported for exons 12-15. Analysis excludes three variants commonly observed in the pseudogene PMS2CL: c.2182_2184delinsG, c.2243_2246delAGAA and deletion of exons 13-14 (chr7:g.6015768_6018727del). POLD1: analysis is limited to chr19:g.50909713 (including c.1433G>A). POLE: analysis is limited to chr12:g.133250250 (including c.1270C>G).